Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells.

Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells.

Genome-wide association studies (GWAS) and subsequent dense-genotyping of associated loci identified over a hundred single-nucleotide polymorphism (SNP) variants associated with the risk of rheumatoid arthritis (RA), type 1 diabetes (T1D), and celiac disease (CeD). Immunological and genetic studies...

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Main Authors: Xinli Hu, Hyun Kim, Towfique Raj, Patrick J Brennan, Gosia Trynka, Nikola Teslovich, Kamil Slowikowski, Wei-Min Chen, Suna Onengut, Clare Baecher-Allan, Philip L De Jager, Stephen S Rich, Barbara E Stranger, Michael B Brenner, Soumya Raychaudhuri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4072514?pdf=render

Internet

http://europepmc.org/articles/PMC4072514?pdf=render

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