DNA damage and reactive nitrogen species are barriers to Vibrio cholerae colonization of the infant mouse intestine.

Ingested Vibrio cholerae pass through the stomach and colonize the small intestines of its host. Here, we show that V. cholerae requires at least two types of DNA repair systems to efficiently compete for colonization of the infant mouse intestine. These results show that V. cholerae experiences inc...

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Bibliographic Details
Main Authors: Bryan W Davies, Ryan W Bogard, Nicole M Dupes, Tyler A I Gerstenfeld, Lyle A Simmons, John J Mekalanos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3040672?pdf=render