The roles of replication-transcription conflict in mutagenesis and evolution of genome organization.

by Jeremy W Schroeder, T Sabari Sankar, Jue D Wang, Lyle A Simmons
Published 2020-08-01

Discovery of a dual protease mechanism that promotes DNA damage checkpoint recovery.

by Peter E Burby, Zackary W Simmons, Jeremy W Schroeder, Lyle A Simmons
Published 2018-07-01

Protein interactions in genome maintenance as novel antibacterial targets.

by Aimee H Marceau, Douglas A Bernstein, Brian W Walsh, Walker Shapiro, Lyle A Simmons, James L Keck
Published 2013-01-01

DNA damage and reactive nitrogen species are barriers to Vibrio cholerae colonization of the infant mouse intestine.

by Bryan W Davies, Ryan W Bogard, Nicole M Dupes, Tyler A I Gerstenfeld, Lyle A Simmons, John J Mekalanos
Published 2011-02-01

DNA methylation from a Type I restriction modification system influences gene expression and virulence in Streptococcus pyogenes.

by Taylor M Nye, Kristin M Jacob, Elena K Holley, Juan M Nevarez, Suzanne Dawid, Lyle A Simmons, Michael E Watson
Published 2019-06-01

Targeting the Type II Secretion System: Development, Optimization, and Validation of a High-Throughput Screen for the Identification of Small Molecule Inhibitors

by Ursula Waack, Tanya L. Johnson, Tanya L. Johnson, Khalil Chedid, Chuanwu Xi, Lyle A. Simmons, Harry L. T. Mobley, Maria Sandkvist
Published 2017-08-01