Transposon insertion profiling by sequencing (TIPseq) for mapping LINE-1 insertions in the human genome

Transposon insertion profiling by sequencing (TIPseq) for mapping LINE-1 insertions in the human genome

Abstract Background Transposable elements make up a significant portion of the human genome. Accurately locating these mobile DNAs is vital to understand their role as a source of structural variation and somatic mutation. To this end, laboratories have developed strategies to selectively amplify or...

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Bibliographic Details
Main Authors: Jared P. Steranka, Zuojian Tang, Mark Grivainis, Cheng Ran Lisa Huang, Lindsay M. Payer, Fernanda O. R. Rego, Thiago Luiz Araujo Miller, Pedro A. F. Galante, Sitharam Ramaswami, Adriana Heguy, David Fenyö, Jef D. Boeke, Kathleen H. Burns
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Mobile DNA
Subjects:
LINE-1
Targeted PCR
Next generation sequencing
Online Access:http://link.springer.com/article/10.1186/s13100-019-0148-5

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http://link.springer.com/article/10.1186/s13100-019-0148-5

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