The Role of Transport Mechanisms in Mycobacterium Tuberculosis Drug Resistance and Tolerance

In the fight against tuberculosis, cell wall permeation of chemotherapeutic agents remains a critical but largely unsolved question. Here we review the major mechanisms of small molecule penetration into and efflux from Mycobacterium tuberculosis and other mycobacteria, and outline how these mechani...

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Bibliographic Details
Main Authors: Jansy Passiflora Sarathy, Véronique Dartois, Edmund Jon Deoon Lee
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/5/11/1210