Structural and Biochemical Features of <i>Eimeria tenella</i> Dihydroorotate Dehydrogenase, a Potential Drug Target

Structural and Biochemical Features of <i>Eimeria tenella</i> Dihydroorotate Dehydrogenase, a Potential Drug Target

Dihydroorotate dehydrogenase (DHODH) is a mitochondrial monotopic membrane protein that plays an essential role in the pyrimidine de novo biosynthesis and electron transport chain pathways. In <i>Eimeria tenella</i>, an intracellular apicomplexan parasite that causes the most severe form...

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Bibliographic Details
Main Authors: Dan Sato, Endah Dwi Hartuti, Daniel Ken Inaoka, Takaya Sakura, Eri Amalia, Madoka Nagahama, Yukina Yoshioka, Naotoshi Tsuji, Tomoyoshi Nozaki, Kiyoshi Kita, Shigeharu Harada, Makoto Matsubayashi, Tomoo Shiba
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Genes
Subjects:
coccidium
apicomplexa
Eimeria tenella
membrane protein
mitochondria
electron transport chain
Online Access:https://www.mdpi.com/2073-4425/11/12/1468

Internet

https://www.mdpi.com/2073-4425/11/12/1468

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