FMN riboswitch aptamer symmetry facilitates conformational switching through mutually exclusive coaxial stacking configurations

FMN riboswitch aptamer symmetry facilitates conformational switching through mutually exclusive coaxial stacking configurations

Knowledge of both apo and holo states of riboswitches aid in elucidating the various mechanisms of ligand-induced conformational “switching” that underpin their gene-regulating capabilities. Previous structural studies on the flavin mononucleotide (FMN)-binding aptamer of the FMN riboswitch, however...

Full description

Bibliographic Details
Main Authors: Haley M. Wilt, Ping Yu, Kemin Tan, Yun-Xing Wang, Jason R. Stagno
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Journal of Structural Biology: X
Subjects:
RNA structure
Riboswitch
Gene regulation
Structural biology
X-ray crystallography
Flavin mononucleotide
Online Access:http://www.sciencedirect.com/science/article/pii/S2590152420300179

Internet

http://www.sciencedirect.com/science/article/pii/S2590152420300179

Similar Items