FMN riboswitch aptamer symmetry facilitates conformational switching through mutually exclusive coaxial stacking configurations

by Haley M. Wilt, Ping Yu, Kemin Tan, Yun-Xing Wang, Jason R. Stagno
Published 2020-01-01

Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL Mpro: insights into enzyme mechanism and drug design

by Daniel W. Kneller, Gwyndalyn Phillips, Hugh M. O'Neill, Kemin Tan, Andrzej Joachimiak, Leighton Coates, Andrey Kovalevsky
Published 2020-11-01

Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains

by Kemin Tan, Min Zhou, Robert P. Jedrzejczak, Ruiying Wu, Raul A. Higuera, Dominika Borek, Gyorgy Babnigg, Andrzej Joachimiak
Published 2020-01-01

Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate

by Hongnan Cao, Kemin Tan, Fengbin Wang, Lance Bigelow, Ragothaman M. Yennamalli, Robert Jedrzejczak, Gyorgy Babnigg, Craig A. Bingman, Andrzej Joachimiak, Madan K. Kharel, Shanteri Singh, Jon S. Thorson, George N. Phillips Jr.
Published 2016-05-01