The development of an effective synthetic route of lesinurad (RDEA594)

Abstract Background Lesinurad is a novel selective uric acid salt transport protein 1 (URAT1) inhibitor which is approved in the USA for the treatment of gout. However, there are some shortcomings among the reported synthetic routes, such as expensive materials, environmental pollution and poor yiel...

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Bibliographic Details
Main Authors: Qing Meng, Tong Zhao, Dongwei Kang, Boshi Huang, Peng Zhan, Xinyong Liu
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Chemistry Central Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13065-017-0316-y