Design, Synthesis, and Acetylcholinesterase Inhibition Assay of Novel 9-(1-(Substituted-benzyl)piperidin-4-yl)-2-chloro-9H-purin-6-amine Derivatives

by Dongwei Kang, Yu'ning Song, Peng Zhan, Qingzhu Zhang, Xinyong Liu
Published 2013-01-01

The development of an effective synthetic route of lesinurad (RDEA594)

by Qing Meng, Tong Zhao, Dongwei Kang, Boshi Huang, Peng Zhan, Xinyong Liu
Published 2017-09-01

Development of a practical synthesis of etravirine via a microwave-promoted amination

by Da Feng, Fenju Wei, Zhao Wang, Dongwei Kang, Peng Zhan, Xinyong Liu
Published 2018-12-01

Regioselective Synthesis of Novel N2- and N4-Substituted 7-Methylpyrazolo[4,5-e][1,2,4]thiadiazines

by Salvador Vega, Maria Teresa Molina, Wenfang Xu, Niangen Chen, Renzhang Yan, Xinyong Liu
Published 2006-11-01

An improved synthesis approach of the HIV-1 inhibitor RDEA427, a pyrrolo[2,3-d]pyrimidine derivative

by Boshi Huang, Xinhao Liu, Wanzhuo Li, Zihui Chen, Dongwei Kang, Peng Zhan, Xinyong Liu
Published 2016-12-01

The development of an effective synthetic route of rilpivirine

by Tao Zhang, Jiapei Yang, Zhongxia Zhou, Zhipeng Fu, Srinivasulu Cherukupalli, Dongwei Kang, Peng Zhan, Xinyong Liu
Published 2021-04-01

Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d]pyrimidine non-nucleoside inhibitors

by Yang Yang, Dongwei Kang, Laura A Nguyen, Zachary B Smithline, Christophe Pannecouque, Peng Zhan, Xinyong Liu, Thomas A Steitz
Published 2018-07-01

Synthesis of Novel Derivatives of 4-Amino-3-(2-Furyl)-5-Mercapto-1,2,4-Triazole as Potential HIV-1 NNRTIs

by Erik De Clercq, Myriam Witvrouw, Christophe Pannecouque, Wenfang Xu, Zhong Li, Defeng Wang, Yuan Cao, Xianchao Cheng, Xinyong Liu, Jingde Wu
Published 2007-08-01

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling

by Yi Zheng, Meng-Wei Zhuang, Lulu Han, Jing Zhang, Mei-Ling Nan, Peng Zhan, Dongwei Kang, Xinyong Liu, Chengjiang Gao, Pei-Hui Wang
Published 2020-12-01

Exploring the hydrophobic channel of NNIBP leads to the discovery of novel piperidine-substituted thiophene[3,2-d]pyrimidine derivatives as potent HIV-1 NNRTIs

by Dongwei Kang, Da Feng, Tiziana Ginex, Jinmi Zou, Fenju Wei, Tong Zhao, Boshi Huang, Yanying Sun, Samuel Desta, Erik De Clercq, Christophe Pannecouque, Peng Zhan, Xinyong Liu
Published 2020-05-01

Identification of Chebulinic Acid and Chebulagic Acid as Novel Influenza Viral Neuraminidase Inhibitors

by Ping Li, Ruikun Du, Ruikun Du, Ruikun Du, Yanyan Wang, Xuewen Hou, Lin Wang, Xiujuan Zhao, Peng Zhan, Xinyong Liu, Lijun Rong, Qinghua Cui, Qinghua Cui, Qinghua Cui
Published 2020-02-01