The antiplatelet agent revacept prevents the increase of systemic thromboxane A2 biosynthesis and neointima hyperplasia

The antiplatelet agent revacept prevents the increase of systemic thromboxane A2 biosynthesis and neointima hyperplasia

Abstract Neointima hyperplasia is a crucial component of restenosis after coronary angioplasty. We have hypothesized that enhanced generation of platelet-derived thromboxane (TX)A2 in response to vascular damage plays a critical role in neointimal hyperplasia and that antiplatelet agents may mitigat...

Full description

Bibliographic Details
Main Authors: Sara Alberti, Qianqian Zhang, Ilaria D’Agostino, Annalisa Bruno, Stefania Tacconelli, Annalisa Contursi, Simone Guarnieri, Melania Dovizio, Lorenza Falcone, Patrizia Ballerini, Götz Münch, Ying Yu, Paola Patrignani
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-77934-x

Internet

https://doi.org/10.1038/s41598-020-77934-x

Similar Items