Revacept, an Inhibitor of Platelet Adhesion in Symptomatic Carotid Artery Stenosis: Design and Rationale of a Randomized Phase II Clinical Trial

by Klaus Gröschel, Timo Uphaus, Ian Loftus, Holger Poppert, Hans Christoph Diener, Jenny Zobel, Götz Münch
Published 2020-10-01

Overexpression of ABCG1 protein attenuates arteriosclerosis and endothelial dysfunction in atherosclerotic rabbits

by Martin Ungerer, Silvia Wagner, Julia Ullrich, Hans-Peter Holthoff, Zhongmin Li, Andreas Bültmann, Götz Münch
Published 2012-06-01

The Scavenger Receptor CD68 Regulates Platelet Mediated Oxidized Low-Density Lipoprotein (oxLDL) Deposition in Atherosclerotic Vessels at an Early Stage of Atherosclerosis in LDLR-...

by Stephan Zeibig, Manuela Büttcher, Silvia Goebel, Jessica Pauli, Annique Hunger, Martin Ungerer, Meinrad Gawaz, Götz Münch
Published 2019-03-01

Combined administration of the GPVI-Fc fusion protein Revacept with low-dose thrombolysis in the treatment of stroke

by Andreas Reimann, Zhongmin Li, Silvia Goebel, Julia Fassbender, Hans-Peter Holthoff, Meinrad Gawaz, Götz Münch, Martin Ungerer
Published 2016-04-01

The GPVI-Fc fusion protein Revacept reduces thrombus formation and improves vascular dysfunction in atherosclerosis without any impact on bleeding times.

by Martin Ungerer, Zhongmin Li, Christine Baumgartner, Silvia Goebel, Jasmin Vogelmann, Hans-Peter Holthoff, Meinrad Gawaz, Götz Münch
Published 2013-01-01

The GPVI-Fc fusion protein Revacept improves cerebral infarct volume and functional outcome in stroke.

by Silvia Goebel, Zhongmin Li, Jasmin Vogelmann, Hans-Peter Holthoff, Heidrun Degen, Dirk M Hermann, Meinrad Gawaz, Martin Ungerer, Götz Münch
Published 2013-01-01

Cyclopeptide COR-1 to treat beta1-adrenergic receptor antibody-induced heart failure.

by Valérie Boivin-Jahns, Kerstin Uhland, Hans-Peter Holthoff, Niklas Beyersdorf, Vladimir Kocoski, Thomas Kerkau, Götz Münch, Martin J Lohse, Martin Ungerer, Roland Jahns
Published 2018-01-01

The antiplatelet agent revacept prevents the increase of systemic thromboxane A2 biosynthesis and neointima hyperplasia

by Sara Alberti, Qianqian Zhang, Ilaria D’Agostino, Annalisa Bruno, Stefania Tacconelli, Annalisa Contursi, Simone Guarnieri, Melania Dovizio, Lorenza Falcone, Patrizia Ballerini, Götz Münch, Ying Yu, Paola Patrignani
Published 2020-12-01

Cross-Linking GPVI-Fc by Anti-Fc Antibodies Potentiates Its Inhibition of Atherosclerotic Plaque- and Collagen-Induced Platelet Activation

by Janina Jamasbi, RPh, Remco T.A. Megens, PhD, Mariaelvy Bianchini, MSc, Kerstin Uhland, PhD, Götz Münch, MD, Martin Ungerer, MD, Shachar Sherman, BSc, Alexander Faussner, PhD, Richard Brandl, MD, Christine John, MSc, Johannes Buchner, PhD, Christian Weber, MD, Reinhard Lorenz, MD, Natalie Elia, PhD, Wolfgang Siess, MD
Published 2016-04-01