Oxidized LDL attenuates apoptosis in monocytic cells by activating ERK signaling

Oxidized LDL attenuates apoptosis in monocytic cells by activating ERK signaling

Low concentrations of oxidized low density lipoprotein (OxLDL) are cytoprotective for phagocytes, although the underlying mechanisms remain unclear. We investigated signaling pathways used by OxLDL to attenuate apoptosis in monocytic cells. OxLDL at 25–50 μg/ml inhibited staurosporine-induced apopto...

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Bibliographic Details
Main Authors: Dmitry Namgaladze, Andreas Kollas, Bernhard Brüne
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
oxidized low density lipoprotein
reactive oxygen species
extracellular signal-regulated kinase
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520428809

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http://www.sciencedirect.com/science/article/pii/S0022227520428809

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