Pharmacological Activation of p53 during Human Monocyte to Macrophage Differentiation Attenuates Their Pro-Inflammatory Activation by TLR4, TLR7 and TLR8 Agonists

by Dmitry Namgaladze, Bernhard Brüne
Published 2021-02-01

ER-Mitochondria Communication in Cells of the Innate Immune System

by Dmitry Namgaladze, Vera Khodzhaeva, Bernhard Brüne
Published 2019-09-01

Oxidized LDL attenuates apoptosis in monocytic cells by activating ERK signaling

by Dmitry Namgaladze, Andreas Kollas, Bernhard Brüne
Published 2008-01-01

Attenuated suppression of the oxidative burst by cells dying in the presence of oxidized low density lipoprotein[S]

by Dmitry Namgaladze, Carla Jennewein, Stefan Preiss, Andreas von Knethen, Bernhard Brüne
Published 2009-11-01

Exploring the Role of ATP-Citrate Lyase in the Immune System

by Monica Dominguez, Bernhard Brüne, Bernhard Brüne, Bernhard Brüne, Bernhard Brüne, Dmitry Namgaladze
Published 2021-02-01

Inhibitors of Oxidative Phosphorylation Modulate Astrocyte Inflammatory Responses through AMPK-Dependent Ptgs2 mRNA Stabilization

by Alina Astakhova, Dmitry Chistyakov, Dominique Thomas, Gerd Geisslinger, Bernhard Brüne, Marina Sergeeva, Dmitry Namgaladze
Published 2019-10-01

Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase

by Dmitry Namgaladze, Sven Zukunft, Frank Schnütgen, Nina Kurrle, Ingrid Fleming, Dominik Fuhrmann, Bernhard Brüne, Bernhard Brüne
Published 2018-12-01

AMP-Activated Protein Kinase Interacts with the Peroxisome Proliferator-Activated Receptor Delta to Induce Genes Affecting Fatty Acid Oxidation in Human Macrophages.

by Marina Kemmerer, Florian Finkernagel, Marcela Frota Cavalcante, Dulcineia Saes Parra Abdalla, Rolf Müller, Bernhard Brüne, Dmitry Namgaladze
Published 2015-01-01

A Novel Function for 15-Lipoxygenases in Cholesterol Homeostasis and CCL17 Production in Human Macrophages

by Ryan G. Snodgrass, Ekaterina Zezina, Dmitry Namgaladze, Sahil Gupta, Carlo Angioni, Gerd Geisslinger, Gerd Geisslinger, Dieter Lütjohann, Bernhard Brüne
Published 2018-08-01

Lysosome-Dependent LXR and PPARδ Activation Upon Efferocytosis in Human Macrophages

by Ana Carolina Mota, Monica Dominguez, Andreas Weigert, Ryan G. Snodgrass, Dmitry Namgaladze, Bernhard Brüne, Bernhard Brüne, Bernhard Brüne, Bernhard Brüne
Published 2021-05-01

Mitofusin 2 Deficiency Causes Pro-Inflammatory Effects in Human Primary Macrophages

by Vera Khodzhaeva, Yannick Schreiber, Gerd Geisslinger, Gerd Geisslinger, Ralf P. Brandes, Bernhard Brüne, Bernhard Brüne, Bernhard Brüne, Bernhard Brüne, Dmitry Namgaladze
Published 2021-08-01

IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors

by Sahil Gupta, Arpit Jain, Shahzad Nawaz Syed, Ryan G. Snodgrass, Beatrice Pflüger-Müller, Matthias S. Leisegang, Andreas Weigert, Ralf P. Brandes, Ingo Ebersberger, Bernhard Brüne, Dmitry Namgaladze
Published 2018-10-01

scFv-Anti-LDL(-)-Metal-Complex Multi-Wall Functionalized-Nanocapsules as a Promising Tool for the Prevention of Atherosclerosis Progression

by Marcela Frota Cavalcante, Márcia Duarte Adorne, Walter Miguel Turato, Marina Kemmerer, Mayara Klimuk Uchiyama, Ana Carolina Cavazzin Asbahr, Aline de Cristo Soares Alves, Sandra Helena Poliselli Farsky, Carine Drewes, Marina Cecília Spatti, Soraya Megumi Kazuma, Marcel Boss, Silvia Stanisçuaski Guterres, Koiti Araki, Bernhard Brüne, Dmitry Namgaladze, Adriana Raffin Pohlmann, Dulcineia Saes Parra Abdalla
Published 2021-04-01

Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells

by Juliane Hitzel, Eunjee Lee, Yi Zhang, Sofia Iris Bibli, Xiaogang Li, Sven Zukunft, Beatrice Pflüger, Jiong Hu, Christoph Schürmann, Andrea Estefania Vasconez, James A. Oo, Adelheid Kratzer, Sandeep Kumar, Flávia Rezende, Ivana Josipovic, Dominique Thomas, Hector Giral, Yannick Schreiber, Gerd Geisslinger, Christian Fork, Xia Yang, Fragiska Sigala, Casey E. Romanoski, Jens Kroll, Hanjoong Jo, Ulf Landmesser, Aldons J. Lusis, Dmitry Namgaladze, Ingrid Fleming, Matthias S. Leisegang, Jun Zhu, Ralf P. Brandes
Published 2018-06-01