Chikungunya virus infection results in higher and persistent viral replication in aged rhesus macaques due to defects in anti-viral immunity.

Chikungunya virus infection results in higher and persistent viral replication in aged rhesus macaques due to defects in anti-viral immunity.

Chikungunya virus (CHIKV) is a re-emerging mosquito-borne Alphavirus that causes a clinical disease involving fever, myalgia, nausea and rash. The distinguishing feature of CHIKV infection is the severe debilitating poly-arthralgia that may persist for several months after viral clearance. Since its...

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Bibliographic Details
Main Authors: Ilhem Messaoudi, Jennifer Vomaske, Thomas Totonchy, Craig N Kreklywich, Kristen Haberthur, Laura Springgay, James D Brien, Michael S Diamond, Victor R Defilippis, Daniel N Streblow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3723534?pdf=render

Internet

http://europepmc.org/articles/PMC3723534?pdf=render

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