Assessment of PI3K/mTOR/AKT Pathway Elements to Serve as Biomarkers and Therapeutic Targets in Penile Cancer

Assessment of PI3K/mTOR/AKT Pathway Elements to Serve as Biomarkers and Therapeutic Targets in Penile Cancer

The PI3K/mTOR/AKT pathway might represent an intriguing option for treatment of penile cancer (PeCa). We aimed to assess whether members of this pathway might serve as biomarkers and targets for systemic therapy. Tissue of primary cancer from treatment-naïve PeCa patients was used for tissue microar...

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Bibliographic Details
Main Authors: Anita Thomas, Sascha Reetz, Philipp Stenzel, Katrin Tagscherer, Wilfried Roth, Mario Schindeldecker, Martin Michaelis, Florian Rothweiler, Jindrich Cinatl, Jaroslav Cinatl, Robert Dotzauer, Olesya Vakhrusheva, Maarten Albersen, Stephan Macher-Goeppinger, Axel Haferkamp, Eva Juengel, Andreas Neisius, Igor Tsaur
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
penile cancer
AKT
mTOR
cell lines
biomarker
targeted therapy
Online Access:https://www.mdpi.com/2072-6694/13/10/2323

Internet

https://www.mdpi.com/2072-6694/13/10/2323

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