Role of Hypoxia and the Adenosine System in Immune Evasion and Prognosis of Patients with Brain Metastases of Melanoma: A Multiplex Whole Slide Immunofluorescence Study

by Arnulf Mayer, Maximilian Haist, Carmen Loquai, Stephan Grabbe, Matthias Rapp, Wilfried Roth, Peter Vaupel, Heinz Schmidberger
Published 2020-12-01

Expression and Functional Characterization of the BNIP3 Protein in Renal Cell Carcinomas

by Stephan Macher-Goeppinger, Martina Keith, Gencay Hatiboglu, Markus Hohenfellner, Peter Schirmacher, Wilfried Roth, Katrin E. Tagscherer
Published 2017-12-01

Harnessing the p53-PUMA Axis to Overcome DNA Damage Resistance in Renal Cell Carcinoma

by Xiaoguang Zhou, Yanis Tolstov, Aysenur Arslan, Wilfried Roth, Carsten Grüllich, Sascha Pahernik, Markus Hohenfellner, Stefan Duensing
Published 2014-12-01

Ex vivo tissue slice culture system to measure drug-response rates of hepatic metastatic colorectal cancer

by Steve Z. Martin, Daniel C. Wagner, Nina Hörner, David Horst, Hauke Lang, Katrin E. Tagscherer, Wilfried Roth
Published 2019-11-01

SWI/SNF-deficient undifferentiated/rhabdoid carcinoma of the gallbladder carrying a POLE mutation in a 30-year-old woman: a case report

by Tiemo S. Gerber, Abbas Agaimy, Arndt Hartmann, Michael Habekost, Wilfried Roth, Albrecht Stenzinger, Peter Schirmacher, Beate K. Straub
Published 2021-06-01

Clinicopathological Significance of Syndecan-1 in Cholangiocarcinoma: A Study Based on Immunohistochemistry and Public Sequencing Data

by Tiemo S. Gerber, Fabian Bartsch, Daniel C. Wagner, Mario Schindeldecker, Lisa-Katharina Heuft, Wilfried Roth, Hauke Lang, Beate K. Straub
Published 2021-06-01

Key Enzymes in Pyrimidine Synthesis, CAD and CPS1, Predict Prognosis in Hepatocellular Carcinoma

by Dirk Andreas Ridder, Mario Schindeldecker, Arndt Weinmann, Kristina Berndt, Lana Urbansky, Hagen Roland Witzel, Stefan Heinrich, Wilfried Roth, Beate Katharina Straub
Published 2021-02-01

Vascular Inflammation and Dysfunction in Lupus-Prone Mice-IL-6 as Mediator of Disease Initiation

by Paul Marczynski, Myriam Meineck, Ning Xia, Huige Li, Daniel Kraus, Wilfried Roth, Tamara Möckel, Simone Boedecker, Andreas Schwarting, Julia Weinmann-Menke
Published 2021-02-01

Comparative analysis of nuclear and mitochondrial DNA from tissue and liquid biopsies of colorectal cancer patients

by Anna Haupts, Anne Vogel, Sebastian Foersch, Monika Hartmann, Annett Maderer, Nicolas Wachter, Tobias Huber, Werner Kneist, Wilfried Roth, Hauke Lang, Markus Moehler, Nils Hartmann
Published 2021-08-01

PD-L1 Expression and Immune Cell Infiltration in Gastroenteropancreatic (GEP) and Non-GEP Neuroendocrine Neoplasms With High Proliferative Activity

by Martina Ferrata, Arno Schad, Stefanie Zimmer, Thomas J. Musholt, Katharina Bahr, Julian Kuenzel, Sven Becker, Erik Springer, Wilfried Roth, Matthias M. Weber, Christian Fottner
Published 2019-05-01

Decoy Receptor 3 Is a Prognostic Factor in Renal Cell Cancer

by Stephan Macher-Goeppinger, Sebastian Aulmann, Nina Wagener, Benjamin Funke, Katrin E. Tagscherer, Axel Haferkamp, Markus Hohenfellner, Sunghee Kim, Frank Autschbach, Peter Schirmacher, Wilfried Roth
Published 2008-10-01

Uncoupling of PUMA Expression and Apoptosis Contributes to Functional Heterogeneity in Renal Cell Carcinoma — Prognostic and Translational Implications

by Xiaoguang Zhou, Jielin Li, Christina Marx, Yanis Tolstov, Geraldine Rauch, Esther Herpel, Stephan Macher-Goeppinger, Wilfried Roth, Carsten Grüllich, Sascha Pahernik, Markus Hohenfellner, Stefan Duensing
Published 2015-12-01

Microsatellite instability and survival after adjuvant chemotherapy among stage II and III colon cancer patients: results from a population‐based study

by Elizabeth Alwers, Lina Jansen, Hendrik Bläker, Matthias Kloor, Katrin E. Tagscherer, Wilfried Roth, Daniel Boakye, Esther Herpel, Carsten Grüllich, Jenny Chang‐Claude, Hermann Brenner, Michael Hoffmeister
Published 2020-02-01

Nivolumab Reduces PD1 Expression and Alters Density and Proliferation of Tumor Infiltrating Immune Cells in a Tissue Slice Culture Model of Renal Cell Carcinoma

by Philipp J. Stenzel, Nina Hörner, Sebastian Foersch, Daniel-Christoph Wagner, Igor Tsaur, Anita Thomas, Axel Haferkamp, Stephan Macher-Goeppinger, Wilfried Roth, Stefan Porubsky, Katrin E. Tagscherer
Published 2021-09-01

Restricted Water Diffusion in Diffusion-Weighted Magnetic Resonance Imaging in Pancreatic Cancer is Associated with Tumor Hypoxia

by Philipp Mayer, Anne Kraft, Hagen R. Witzel, Nicole Marnet, Nina Hörner, Wilfried Roth, Stefan Heinrich, Thilo Hackert, Frank Bergmann, Hans-Ulrich Kauczor, Miriam Klauss, Matthias M. Gaida
Published 2021-12-01

Prognostic and Predictive Value of Tumor-infiltrating Leukocytes and of Immune Checkpoint Molecules PD1 and PDL1 in Clear Cell Renal Cell Carcinoma

by Philipp J. Stenzel, Mario Schindeldecker, Katrin E. Tagscherer, Sebastian Foersch, Esther Herpel, Markus Hohenfellner, Gencay Hatiboglu, Juergen Alt, Christian Thomas, Axel Haferkamp, Wilfried Roth, Stephan Macher-Goeppinger
Published 2020-02-01

Young-onset gastric cancer and Epstein–Barr Virus (EBV) – a major player in the pathogenesis?

by Assaf Moore, Elad Hikri, Tal Goshen-Lago, Tamar Barkan, Sara Morgenstern, Elena Brook, Annett Maderer, Wilfried Roth, Noa Gordon, Hanoch Kashtan, Baruch Brenner, Markus Moehler, Irit Ben Aharon
Published 2020-01-01

External validation of molecular subtype classifications of colorectal cancer based on microsatellite instability, CIMP, BRAF and KRAS

by Elizabeth Alwers, Hendrik Bläker, Viola Walter, Lina Jansen, Matthias Kloor, Alexander Arnold, Julia Sieber-Frank, Esther Herpel, Katrin E. Tagscherer, Wilfried Roth, Jenny Chang-Claude, Hermann Brenner, Michael Hoffmeister
Published 2019-07-01

Alterations in ERBB2 and BRCA and microsatellite instability as new personalized treatment options in small bowel carcinoma

by Alexander Quaas, Carina Heydt, Dirk Waldschmidt, Hakan Alakus, Thomas Zander, Tobias Goeser, Philipp Kasper, Christiane Bruns, Anna Brunn, Wilfried Roth, Nils Hartmann, Anne Bunck, Matthias Schmidt, Reinhard Buettner, Sabine Merkelbach-Bruse
Published 2019-02-01

Distinct Activities of Glycolytic Enzymes Identify Chronic Lymphocytic Leukemia Patients with a more Aggressive Course and Resistance to Chemo-Immunotherapy

by Georg Gdynia, Tadeusz Robak, Jürgen Kopitz, Anette Heller, Svetlana Grekova, Katarina Duglova, Gloria Laukemper, Monika Heinzel-Gutenbrunner, Cornelius Gutenbrunner, Wilfried Roth, Anthony D. Ho, Peter Schirmacher, Michael Schmitt, Peter Dreger, Leopold Sellner
Published 2018-06-01