Self-Nanoemulsifying Drug Delivery System Loaded with Psiadia punctulata Major Metabolites for Hypertensive Emergencies: Effect on Hemodynamics and Cardiac Conductance

Self-Nanoemulsifying Drug Delivery System Loaded with Psiadia punctulata Major Metabolites for Hypertensive Emergencies: Effect on Hemodynamics and Cardiac Conductance

Vasodilators are an important class of antihypertensive agents. However, they have limited clinical use due to the reflex tachycardia associated with their use which masks most of its antihypertensive effect and raises cardiac risk. Chemical investigation of Psiadia punctulata afforded five major me...

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Bibliographic Details
Main Authors: Hossam M. Abdallah, Hany M. El-Bassossy, Ali M. El-Halawany, Tarek A. Ahmed, Gamal A. Mohamed, Azizah M. Malebari, Noura A. Hassan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
methoxy flavonoids
umuhengerin
reflex tachycardia
vasodilators
SNEDDS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.681070/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.681070/full

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