Synthesis, Anti-proliferative Activity, and Molecular Docking Study of New Series of 1,3-5-Triazine Schiff Base Derivatives

by Hessa H. Al Rasheed, Azizah M. Malebari, Kholood A. Dahlous, Darren Fayne, Ayman El-Faham
Published 2020-09-01

Synthesis of New 1, 3, 4-Oxadiazole-Incorporated 1, 2, 3-Triazole Moieties as Potential Anticancer Agents Targeting Thymidylate Synthase and Their Docking Studies

by Mohammad Mahboob Alam, Abdulraheem SA Almalki, Thikryat Neamatallah, Nada M. Ali, Azizah M. Malebari, Syed Nazreen
Published 2020-11-01

The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme

by Azizah M. Malebari, Tarek S. Ibrahim, Ibrahim M. Salem, Ismail Salama, Ahdab N. Khayyat, Samia M. Mostafa, Osama I. El-Sabbagh, Khaled M. Darwish
Published 2020-09-01

Nitric-Oxide-Mediated Vasodilation of Bioactive Compounds Isolated from <i>Hypericum revolutum</i> in Rat Aorta

by Hossam M. Abdallah, Noha Z. Timraz, Sabrin R. M. Ibrahim, Ali M. El-Halawany, Azizah M. Malebari, Ibrahim A. Shehata, Hany M. El-Bassossy
Published 2021-06-01

<i>Euphorbia</i> <i>cuneata</i> Represses LPS-induced Acute Lung Injury in Mice via its Antioxidative and Anti-inflammatory Activities

by Hossam M. Abdallah, Dina S. El‑Agamy, Sabrin R. M. Ibrahim, Gamal A. Mohamed, Wael M. Elsaed, Amjad A. Elghamdi, Martin K. Safo, Azizah M. Malebari
Published 2020-11-01

The Antiproliferative and Apoptotic Effect of a Novel Synthesized <i>S</i>-Triazine Dipeptide Series, and Toxicity Screening in Zebrafish Embryos

by Azizah M. Malebari, Rakia Abd Alhameed, Zainab Almarhoon, Muhammad Farooq, Mohammad A. M. Wadaan, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio, Ayman El-Faham
Published 2021-02-01

Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect

by Tarek S. Ibrahim, Mohamed M. Hawwas, Azizah M. Malebari, Ehab S. Taher, Abdelsattar M. Omar, Thikryat Neamatallah, Zakaria K. Abdel-Samii, Martin K. Safo, Yaseen A. M. M. Elshaier
Published 2021-01-01

Osteoprotective Activity and Metabolite Fingerprint via UPLC/MS and GC/MS of <i>Lepidium sativum</i> in Ovariectomized Rats

by Hossam M. Abdallah, Mohamed A. Farag, Mardi M. Algandaby, Mohammed Z. Nasrullah, Ashraf B. Abdel-Naim, Basma G. Eid, Martin K. Safo, Abdulrahman E. Koshak, Azizah M. Malebari
Published 2020-07-01

Potent Quinoline-Containing Combretastatin A-4 Analogues: Design, Synthesis, Antiproliferative, and Anti-Tubulin Activity

by Tarek S. Ibrahim, Mohamed M. Hawwas, Azizah M. Malebari, Ehab S. Taher, Abdelsattar M. Omar, Niamh M. O’Boyle, Eavan McLoughlin, Zakaria K. Abdel-Samii, Yaseen A. M. M. Elshaier
Published 2020-11-01

Synthesis and Biological Evaluation of 1,2,3-Triazole Tethered Thymol-1,3,4-Oxadiazole Derivatives as Anticancer and Antimicrobial Agents

by Abdulraheem S. A. Almalki, Syed Nazreen, Azizah M. Malebari, Nada M. Ali, Ahmed A. Elhenawy, Abdullah A. A. Alghamdi, Abrar Ahmad, Sulaiman Y. M. Alfaifi, Meshari A. Alsharif, Mohammad Mahboob Alam
Published 2021-08-01

3-Vinylazetidin-2-Ones: Synthesis, Antiproliferative and Tubulin Destabilizing Activity in MCF-7 and MDA-MB-231 Breast Cancer Cells

by Shu Wang, Azizah M. Malebari, Thomas F. Greene, Niamh M. O’Boyle, Darren Fayne, Seema M. Nathwani, Brendan Twamley, Thomas McCabe, Niall O. Keely, Daniela M. Zisterer, Mary J. Meegan
Published 2019-04-01

Naproxen Based 1,3,4-Oxadiazole Derivatives as EGFR Inhibitors: Design, Synthesis, Anticancer, and Computational Studies

by Mohammad Mahboob Alam, Syed Nazreen, Abdulraheem S. A. Almalki, Ahmed A. Elhenawy, Nawaf I. Alsenani, Serag Eldin I. Elbehairi, Azizah M. Malebari, Mohammad Y. Alfaifi, Meshari A. Alsharif, Sulaiman Y. M. Alfaifi
Published 2021-08-01

Self-Nanoemulsifying Drug Delivery System Loaded with Psiadia punctulata Major Metabolites for Hypertensive Emergencies: Effect on Hemodynamics and Cardiac Conductance

by Hossam M. Abdallah, Hossam M. Abdallah, Hany M. El-Bassossy, Ali M. El-Halawany, Tarek A. Ahmed, Tarek A. Ahmed, Gamal A. Mohamed, Gamal A. Mohamed, Azizah M. Malebari, Noura A. Hassan
Published 2021-06-01

Synthesis and Biological Evaluation of 1‑(Diarylmethyl)‑1<i>H</i>‑1,2,4‑Triazoles and 1‑(Diarylmethyl)‑1<i>H</i>‑Imidazoles as a Novel Class of Anti-Mitotic Agent for Activity in B...

by Gloria Ana, Patrick M. Kelly, Azizah M. Malebari, Sara Noorani, Seema M. Nathwani, Brendan Twamley, Darren Fayne, Niamh M. O’Boyle, Daniela M. Zisterer, Elisangela Flavia Pimentel, Denise Coutinho Endringer, Mary J. Meegan
Published 2021-02-01

In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors

by Tarek S. Ibrahim, Ehab S. Taher, Ebtihal Samir, Azizah M. Malebari, Ahdab N. Khayyat, Mamdouh F. A. Mohamed, Riham M. Bokhtia, Mohammed A. AlAwadh, Israa A. Seliem, Hani Z. Asfour, Nabil A. Alhakamy, Siva S. Panda, Amany M.M. AL-Mahmoudy
Published 2020-07-01