Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells.

Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells.

Apelin is a peptide ligand for an orphan G-protein coupled receptor (APJ receptor) and serves as a critical gradient for migration of mesodermal cells fated to contribute to the myocardial lineage. The present study was designed to establish a robust cardiac differentiation protocol, specifically, t...

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Bibliographic Details
Main Authors: I-Ning E Wang, Xiang Wang, Xiaohu Ge, Joshua Anderson, Michael Ho, Euan Ashley, Jianwei Liu, Manish J Butte, Masayuki Yazawa, Ricardo E Dolmetsch, Thomas Quertermous, Phillip C Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3365885?pdf=render

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http://europepmc.org/articles/PMC3365885?pdf=render

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