TrpC3 regulates hypertrophy-associated gene expression without affecting myocyte beating or cell size.

by Jacob S Brenner, Ricardo E Dolmetsch
Published 2007-08-01

A promoter in the coding region of the calcium channel gene CACNA1C generates the transcription factor CCAT.

by Natalia Gomez-Ospina, Georgia Panagiotakos, Thomas Portmann, Sergiu P Pasca, Dania Rabah, Agata Budzillo, Jean Pierre Kinet, Ricardo E Dolmetsch
Published 2013-01-01

Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome

by Georgia Panagiotakos, Christos Haveles, Arpana Arjun, Ralitsa Petrova, Anshul Rana, Thomas Portmann, Sergiu P Paşca, Theo D Palmer, Ricardo E Dolmetsch
Published 2019-12-01

Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells.

by I-Ning E Wang, Xiang Wang, Xiaohu Ge, Joshua Anderson, Michael Ho, Euan Ashley, Jianwei Liu, Manish J Butte, Masayuki Yazawa, Ricardo E Dolmetsch, Thomas Quertermous, Phillip C Yang
Published 2012-01-01

16p11.2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development

by Julien G Roth, Kristin L Muench, Aditya Asokan, Victoria M Mallett, Hui Gai, Yogendra Verma, Stephen Weber, Carol Charlton, Jonas L Fowler, Kyle M Loh, Ricardo E Dolmetsch, Theo D Palmer
Published 2020-11-01

A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients

by Yishan Sun, Sergiu P Paşca, Thomas Portmann, Carleton Goold, Kathleen A Worringer, Wendy Guan, Karen C Chan, Hui Gai, Daniel Vogt, Ying-Jiun J Chen, Rong Mao, Karrie Chan, John LR Rubenstein, Daniel V Madison, Joachim Hallmayer, Wendy M Froehlich-Santino, Jonathan A Bernstein, Ricardo E Dolmetsch
Published 2016-07-01

Behavioral Abnormalities and Circuit Defects in the Basal Ganglia of a Mouse Model of 16p11.2 Deletion Syndrome

by Thomas Portmann, Mu Yang, Rong Mao, Georgia Panagiotakos, Jacob Ellegood, Gul Dolen, Patrick L. Bader, Brad A. Grueter, Carleton Goold, Elaine Fisher, Katherine Clifford, Pavitra Rengarajan, David Kalikhman, Darren Loureiro, Nay L. Saw, Zhou Zhengqui, Michael A. Miller, Jason P. Lerch, R. Mark Henkelman, Mehrdad Shamloo, Robert C. Malenka, Jacqueline N. Crawley, Ricardo E. Dolmetsch
Published 2014-05-01