Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells.

Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells.

BACKGROUND:Pluripotent embryonic stem (ES) cells, which have the capacity to give rise to all tissue types in the body, show great promise as a versatile source of cells for regenerative therapy. However, the basic mechanisms of lineage specification of pluripotent stem cells are largely unknown, an...

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Bibliographic Details
Main Authors: Jijun Hao, Marie A Daleo, Clare K Murphy, Paul B Yu, Joshua N Ho, Jianyong Hu, Randall T Peterson, Antonis K Hatzopoulos, Charles C Hong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2483414?pdf=render

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http://europepmc.org/articles/PMC2483414?pdf=render

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