Multi-Step Usage of in Vivo Models During Rational Drug Design and Discovery

by Charles H. Williams, Charles C. Hong
Published 2011-04-01

Zebrafish small molecule screens: Taking the phenotypic plunge

by Charles H. Williams, Charles C. Hong
Published 2016-01-01

Bone morphogenetic protein type I receptor antagonists decrease growth and induce cell death of lung cancer cell lines.

by Elaine Langenfeld, Charles C Hong, Gandhi Lanke, John Langenfeld
Published 2013-01-01

DMH1, a novel BMP small molecule inhibitor, increases cardiomyocyte progenitors and promotes cardiac differentiation in mouse embryonic stem cells.

by Ada Ao, Jijun Hao, Corey R Hopkins, Charles C Hong
Published 2012-01-01

Autotaxin signaling governs phenotypic heterogeneity in visceral and parietal mesothelia.

by Elaine L Shelton, Cristi L Galindo, Charles H Williams, Elise Pfaltzgraff, Charles C Hong, David M Bader
Published 2013-01-01

Baseline cardiometabolic profiles and SARS-CoV-2 infection in the UK Biobank.

by Ryan J Scalsky, Yi-Ju Chen, Karan Desai, Jeffery R O'Connell, James A Perry, Charles C Hong
Published 2021-01-01

BMP pathway regulation of and by macrophages.

by Megha Talati, James West, Rinat Zaynagetdinov, Charles C Hong, Wei Han, Tom Blackwell, Linda Robinson, Timothy S Blackwell, Kirk Lane
Published 2014-01-01

Serial Observations and Mutational Analysis of an Adoptee with Family History of Hypertrophic Cardiomyopathy

by Bronwyn Harris, Jean P. Pfotenhauer, Cheri A. Silverstein, Larry W. Markham, Kim Schafer, Vernat J. Exil, Charles C. Hong
Published 2010-01-01

Familial dilated cardiomyopathy associated with congenital defects in the setting of a novel VCL mutation (Lys815Arg) in conjunction with a known MYPBC3 variant

by Quinn S. Wells, Natalie L. Ausborn, Birgit H. Funke, Jean P. Pfotenhauer, Joseph L. Fredi, Samantha Baxter, Thomas G. DiSalvo, Charles C. Hong
Published 2011-08-01

Bone Morphogenetic Proteins stimulate mammary fibroblasts to promote mammary carcinoma cell invasion.

by Philip Owens, Hannah Polikowsky, Michael W Pickup, Agnieszka E Gorska, Bojana Jovanovic, Aubie K Shaw, Sergey V Novitskiy, Charles C Hong, Harold L Moses
Published 2013-01-01

Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells.

by Jijun Hao, Marie A Daleo, Clare K Murphy, Paul B Yu, Joshua N Ho, Jianyong Hu, Randall T Peterson, Antonis K Hatzopoulos, Charles C Hong
Published 2008-08-01

Selective Small Molecule Targeting β-Catenin Function Discovered by In Vivo Chemical Genetic Screen

by Jijun Hao, Ada Ao, Li Zhou, Clare K. Murphy, Audrey Y. Frist, Jessica J. Keel, Curtis A. Thorne, Kwangho Kim, Ethan Lee, Charles C. Hong
Published 2013-09-01

High-Throughput Screening of Myometrial Calcium-Mobilization to Identify Modulators of Uterine Contractility.

by Jennifer L Herington, Daniel R Swale, Naoko Brown, Elaine L Shelton, Hyehun Choi, Charles H Williams, Charles C Hong, Bibhash C Paria, Jerod S Denton, Jeff Reese
Published 2015-01-01

An In Vivo Chemical Genetic Screen Identifies Phosphodiesterase 4 as a Pharmacological Target for Hedgehog Signaling Inhibition

by Charles H. Williams, Jonathan E. Hempel, Jijun Hao, Audrey Y. Frist, Michelle M. Williams, Jonathan T. Fleming, Gary A. Sulikowski, Michael K. Cooper, Chin Chiang, Charles C. Hong
Published 2015-04-01

PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper

by Asad A. Aboud, Andrew M. Tidball, Kevin K. Kumar, M. Diana Neely, Bingying Han, Kevin C. Ess, Charles C. Hong, Keith M. Erikson, Peter Hedera, Aaron B. Bowman
Published 2015-01-01

BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model

by SongTing Shi, Willem M.H. Hoogaars, David J.J. de Gorter, Sandra H. van Heiningen, Herbert Y. Lin, Charles C. Hong, Dwi U. Kemaladewi, Annemieke Aartsma-Rus, Peter ten Dijke, Peter A.C. 't Hoen
Published 2011-02-01

Correction: Combinatorial Polymer Electrospun Matrices Promote Physiologically-Relevant Cardiomyogenic Stem Cell Differentiation

by Mukesh K. Gupta, Joel M. Walthall, Raghav Venkataraman, Spencer W. Crowder, Dae Kwang Jung, Shann S. Yu, Tromondae K. Feaster, Xintong Wang, Todd D. Giorgio, Charles C. Hong, Franz J. Baudenbacher, Antonis K. Hatzopoulos, Hak-Joon Sung
Published 2012-01-01

Correction: Combinatorial Polymer Electrospun Matrices Promote Physiologically-Relevant Cardiomyogenic Stem Cell Differentiation.

by Mukesh K. Gupta, Joel M. Walthall, Raghav Venkataraman, Spencer W. Crowder, Dae Kwang Jung, Shann S. Yu, Tromondae K. Feaster, Xintong Wang, Todd D. Giorgio, Charles C. Hong, Franz J. Baudenbacher, Antonis K. Hatzopoulos, Hak-Joon Sung
Published 2012-01-01

Combinatorial polymer electrospun matrices promote physiologically-relevant cardiomyogenic stem cell differentiation.

by Mukesh K Gupta, Joel M Walthall, Raghav Venkataraman, Spencer W Crowder, Dae Kwang Jung, Shann S Yu, Tromondae K Feaster, Xintong Wang, Todd D Giorgio, Charles C Hong, Franz J Baudenbacher, Antonis K Hatzopoulos, Hak-Joon Sung
Published 2011-01-01

21st Century Cardio-Oncology

by Calvin Chen Sheng, MD, Laleh Amiri-Kordestani, MD, Todd Palmby, PhD, Thomas Force, MD, Charles C. Hong, MD, PhD, Joseph C. Wu, MD, PhD, Kevin Croce, MD, PhD, Geoffrey Kim, MD, Javid Moslehi, MD
Published 2016-08-01