In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice.

Xenograft mouse models represent helpful tools for preclinical studies on human tumors. For modeling the complexity of the human disease, primary tumor cells are by far superior to established cell lines. As qualified exemplary model, patients' acute lymphoblastic leukemia cells reliably engraf...

Full description

Bibliographic Details
Main Authors: Nadia Terziyska, Catarina Castro Alves, Volker Groiss, Katja Schneider, Katarina Farkasova, Manfred Ogris, Ernst Wagner, Harald Ehrhardt, Renier J Brentjens, Udo zur Stadt, Martin Horstmann, Leticia Quintanilla-Martinez, Irmela Jeremias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3534096?pdf=render