Tumor RAS Gene Expression Levels Are Influenced by the Mutational Status of RAS Genes and Both Upstream and Downstream RAS Pathway Genes

The 3 human RAS genes play pivotal roles regulating proliferation, differentiation, and survival in normal cells and become mutated in 15% to 20% of all human tumors and amplified in many others. In this report, we examined data from The Cancer Genome Atlas to investigate the relationship between RA...

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Bibliographic Details
Main Authors: Robert M Stephens, Ming Yi, Bailey Kessing, Dwight V Nissley, Frank McCormick
Format: Article
Language:English
Published: SAGE Publishing 2017-06-01
Series:Cancer Informatics
Online Access:https://doi.org/10.1177/1176935117711944