Regulators of Homologous Recombination Repair as Novel Targets for Cancer Treatment
To cope with DNA damage, cells possess a complex signaling network called the ‘DNA damage response’ (DDR), which coordinates cell cycle control with DNA repair. The importance of this network is underscored by the cancer predisposition that frequently goes along with hereditary mutations in DNA repa...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-03-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00096/full |