Involvement of Wiskott-Aldrich Syndrome Protein Family Verprolin- Homologous Protein (WAVE) and Rac1 in the Phagocytosis of Amyloid- β(1 – 42) in Rat Microglia

Involvement of Wiskott-Aldrich Syndrome Protein Family Verprolin- Homologous Protein (WAVE) and Rac1 in the Phagocytosis of Amyloid- β(1 – 42) in Rat Microglia

Alzheimer’s disease (AD) is characterized by the accumulation of extracellular amyloid-β (Aβ) fibrils with microglia. Recently, there has been great interest in the microglial phagocytosis of Aβ, because the microglial pathway is considered to be one of the Aβ clearance pathways in the brain parench...

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Bibliographic Details
Main Authors: Yoshihisa Kitamura, Keiichi Shibagaki, Kazuyuki Takata, Daiju Tsuchiya, Takashi Taniguchi, Peter J. Gebicke-Haerter, Hiroaki Miki, Tadaomi Takenawa, Shun Shimohama
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319326738

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http://www.sciencedirect.com/science/article/pii/S1347861319326738

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