The D299G/T399I Toll-like receptor 4 variant associates with body and liver fat: results from the TULIP and METSIM Studies.

The D299G/T399I Toll-like receptor 4 variant associates with body and liver fat: results from the TULIP and METSIM Studies.

BACKGROUND: Toll-like-receptor 4 (TLR) is discussed to provide a molecular link between obesity, inflammation and insulin resistance. Genetic studies with replications in non-diabetic individuals in regard to their fat distribution or insulin resistance according to their carrier status of a common...

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Main Authors: Peter Weyrich, Harald Staiger, Alena Stančáková, Fausto Machicao, Jürgen Machann, Fritz Schick, Norbert Stefan, Johanna Kuusisto, Markku Laakso, Silke Schäfer, Andreas Fritsche, Hans-Ulrich Häring
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2981584?pdf=render

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http://europepmc.org/articles/PMC2981584?pdf=render

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