A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation
Metabolic specialization among major brain cell types is central to nervous system function and determined in large part by the cellular distribution of enzymes. Serine hydrolases are a diverse enzyme class that plays fundamental roles in CNS metabolism and signaling. Here, we perform an activity-ba...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-01-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/12345 |