Multiplexed proteomic profiling of cysteine reactivity and ligandability in human T cells

by Ekaterina V. Vinogradova, Benjamin F. Cravatt
Published 2021-06-01

An anatomical and temporal portrait of physiological substrates for fatty acid amide hydrolase[S]

by Jonathan Z. Long, Melanie LaCava, Xin Jin, Benjamin F. Cravatt
Published 2011-02-01

Targeted disruption of the PME-1 gene causes loss of demethylated PP2A and perinatal lethality in mice.

by Silvia Ortega-Gutiérrez, Donmienne Leung, Scott Ficarro, Eric C Peters, Benjamin F Cravatt
Published 2008-07-01

Activity-based labeling of matrix metalloproteinases in living vertebrate embryos.

by Jonathan Y Keow, Eric D Pond, Justin S Cisar, Benjamin F Cravatt, Bryan D Crawford
Published 2012-01-01

Biomarkers of endocannabinoid system activation in severe obesity.

by Jack C Sipe, T Michael Scott, Sarah Murray, Olivier Harismendy, Gabriel M Simon, Benjamin F Cravatt, Jill Waalen
Published 2010-01-01

Fatty acid amide hydrolase (FAAH) inhibitors exert pharmacological effects, but lack antinociceptive efficacy in rats with neuropathic spinal cord injury pain.

by Aldric T Hama, Peter Germano, Matthew S Varghese, Benjamin F Cravatt, G Todd Milne, James P Pearson, Jacqueline Sagen
Published 2014-01-01

A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation

by Andreu Viader, Daisuke Ogasawara, Christopher M Joslyn, Manuel Sanchez-Alavez, Simone Mori, William Nguyen, Bruno Conti, Benjamin F Cravatt
Published 2016-01-01

Monoacylglycerol Lipase Regulates Fever Response.

by Manuel Sanchez-Alavez, William Nguyen, Simone Mori, Gianluca Moroncini, Andreu Viader, Daniel K Nomura, Benjamin F Cravatt, Bruno Conti
Published 2015-01-01

Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometry

by Allan Weber, Jinsong Ni, Kah-Hiing John Ling, Andrew Acheampong, Diane D-S. Tang-Liu, Robert Burk, Benjamin F. Cravatt, David Woodward
Published 2004-04-01

Endocannabinoids regulate the activity of astrocytic hemichannels and the microglial response against an injury: In vivo studies

by Carmen Vázquez, Rosa María Tolón, María Ruth Pazos, Marta Moreno, Erin C. Koester, Benjamin F. Cravatt, Cecilia J. Hillard, Julián Romero
Published 2015-07-01

Multicomponent mapping of boron chemotypes furnishes selective enzyme inhibitors

by Joanne Tan, Armand B. Cognetta III, Diego B. Diaz, Kenneth M. Lum, Shinya Adachi, Soumajit Kundu, Benjamin F. Cravatt, Andrei K. Yudin
Published 2017-11-01

Synthesis and Sulfur Electrophilicity of the Nuphar Thiaspirane Pharmacophore

by Norihiro Tada, Daniel J. Jansen, Matthew P. Mower, Megan M. Blewett, Jeffrey C. Umotoy, Benjamin F. Cravatt, Dennis W. Wolan, Ryan A. Shenvi
Published 2016-06-01

ABHD4-dependent developmental anoikis safeguards the embryonic brain

by Zsófia I. László, Zsolt Lele, Miklós Zöldi, Vivien Miczán, Fruzsina Mógor, Gabriel M. Simon, Ken Mackie, Imre Kacskovics, Benjamin F. Cravatt, István Katona
Published 2020-08-01

The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activity

by Sachin Patel, Erica J. Carrier, W-S. Vanessa Ho, David J. Rademacher, Sonya Cunningham, D. Sudarshan Reddy, J.R. Falck, Benjamin F. Cravatt, Cecilia J. Hillard
Published 2005-02-01

Selective inhibition of monoacylglycerol lipase is associated with passive coping behavior and attenuation of stress-induced dopamine release in the medial prefrontal cortex

by Francisco Javier Pavón, Ilham Y. Polis, David G. Stouffer, Benjamin F. Cravatt, Marisa Roberto, Rémi Martin-Fardon, Fernando Rodríguez de Fonseca, Loren H. Parsons, Antonia Serrano
Published 2021-05-01

ThermoMouse: An In Vivo Model to Identify Modulators of UCP1 Expression in Brown Adipose Tissue

by Andrea Galmozzi, Si B. Sonne, Svetlana Altshuler-Keylin, Yutaka Hasegawa, Kosaku Shinoda, Ineke H.N. Luijten, Jae Won Chang, Louis Z. Sharp, Benjamin F. Cravatt, Enrique Saez, Shingo Kajimura
Published 2014-12-01

Translation attenuation by minocycline enhances longevity and proteostasis in old post-stress-responsive organisms

by Gregory M Solis, Rozina Kardakaris, Elizabeth R Valentine, Liron Bar-Peled, Alice L Chen, Megan M Blewett, Mark A McCormick, James R Williamson, Brian Kennedy, Benjamin F Cravatt, Michael Petrascheck
Published 2018-11-01

Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism

by Nora Kory, Susanne Grond, Siddhesh S. Kamat, Zhihuan Li, Natalie Krahmer, Chandramohan Chitraju, Ping Zhou, Florian Fröhlich, Ivana Semova, Christer Ejsing, Rudolf Zechner, Benjamin F. Cravatt, Robert V. Farese, Jr., Tobias C. Walther
Published 2017-01-01

Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action

by Andreu Viader, Jacqueline L. Blankman, Peng Zhong, Xiaojie Liu, Joel E. Schlosburg, Christopher M. Joslyn, Qing-Song Liu, Aaron J. Tomarchio, Aron H. Lichtman, Dana E. Selley, Laura J. Sim-Selley, Benjamin F. Cravatt
Published 2015-08-01

Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1...

by Alexis F. League, Benjamin L. Gorman, Douglas J. Hermes, Clare T. Johnson, Ian R. Jacobs, Barkha J. Yadav-Samudrala, Justin L. Poklis, Micah J. Niphakis, Benjamin F. Cravatt, Aron H. Lichtman, Bogna M. Ignatowska-Jankowska, Sylvia Fitting
Published 2021-08-01