Polyamines inhibit porin-mediated fluoroquinolone uptake in mycobacteria.

Polyamines decrease the permeability of the outer membrane of Escherichia coli to fluoroquinolones and β-lactams. In this study, we tested the effect of four polyamines (spermidine, spermine, cadaverine and putrescine) on fluoroquinolone uptake in Mycobacterium bovis BCG. Our results show that polya...

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Bibliographic Details
Main Authors: Jansy Passiflora Sarathy, Edmund Lee, Véronique Dartois
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23755283/?tool=EBI