New Challenges in Tumor Mutation Heterogeneity in Advanced Ovarian Cancer by a Targeted Next-Generation Sequencing (NGS) Approach

New Challenges in Tumor Mutation Heterogeneity in Advanced Ovarian Cancer by a Targeted Next-Generation Sequencing (NGS) Approach

Next-generation sequencing (NGS) technology has advanced knowledge of the genomic landscape of ovarian cancer, leading to an innovative molecular classification of the disease. However, patient survival and response to platinum-based treatments are still not predictable based on the tumor genetic pr...

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Bibliographic Details
Main Authors:	Marica Garziera, Rossana Roncato, Marcella Montico, Elena De Mattia, Sara Gagno, Elena Poletto, Simona Scalone, Vincenzo Canzonieri, Giorgio Giorda, Roberto Sorio, Erika Cecchin, Giuseppe Toffoli
Format:	Article
Language:	English
Published:	MDPI AG 2019-06-01
Series:	Cells
Subjects:	advanced ovarian cancer HGSOC NGS tumor profile concurrent somatic mutations <i>TP53</i> platinum sensitivity driver actionable genes translational medicine
Online Access:	https://www.mdpi.com/2073-4409/8/6/584

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