Germline and Somatic Pharmacogenomics to Refine Rectal Cancer Patients Selection for Neo-Adjuvant Chemoradiotherapy

by Elena De Mattia, Rossana Roncato, Elisa Palazzari, Giuseppe Toffoli, Erika Cecchin
Published 2020-06-01

Pharmacogenomics of Targeted Agents for Personalization of Colorectal Cancer Treatment

by Alessia Bignucolo, Elena De Mattia, Erika Cecchin, Rossana Roncato, Giuseppe Toffoli
Published 2017-07-01

Circulating-Free DNA Analysis in Hepatocellular Carcinoma: A Promising Strategy to Improve Patients’ Management and Therapy Outcomes

by Silvia Mezzalira, Elena De Mattia, Michela Guardascione, Chiara Dalle Fratte, Erika Cecchin, Giuseppe Toffoli
Published 2019-11-01

The Molecular and Microenvironmental Landscape of Glioblastomas: Implications for the Novel Treatment Choices

by Federica Di Cintio, Federica Di Cintio, Michele Dal Bo, Lorena Baboci, Elena De Mattia, Maurizio Polano, Giuseppe Toffoli
Published 2020-11-01

rs4143815-<i>PDL1</i>, a New Potential Immunogenetic Biomarker of Biochemical Recurrence in Locally Advanced Prostate Cancer after Radiotherapy

by Chiara Zanusso, Eva Dreussi, Roberto Bortolus, Chiara Romualdi, Sara Gagno, Elena De Mattia, Loredana Romanato, Franca Sartor, Luca Quartuccio, Erika Cecchin, Giuseppe Toffoli
Published 2019-04-01

HLA-G 3′UTR Polymorphisms Predict Drug-Induced G3-4 Toxicity Related to Folinic Acid/5-Fluorouracil/Oxaliplatin (FOLFOX4) Chemotherapy in Non-Metastatic Colorectal Cancer

by Marica Garziera, Saverio Virdone, Elena De Mattia, Lucia Scarabel, Erika Cecchin, Jerry Polesel, Mario D’Andrea, Nicoletta Pella, Angela Buonadonna, Adolfo Favaretto, Giuseppe Toffoli
Published 2017-06-01

New Challenges in Tumor Mutation Heterogeneity in Advanced Ovarian Cancer by a Targeted Next-Generation Sequencing (NGS) Approach

by Marica Garziera, Rossana Roncato, Marcella Montico, Elena De Mattia, Sara Gagno, Elena Poletto, Simona Scalone, Vincenzo Canzonieri, Giorgio Giorda, Roberto Sorio, Erika Cecchin, Giuseppe Toffoli
Published 2019-06-01

Clonal Evolution of <i>TP53</i> c.375+1G&gt;A Mutation in Pre- and Post- Neo-Adjuvant Chemotherapy (NACT) Tumor Samples in High-Grade Serous Ovarian Cancer (HGSOC)

by Marica Garziera, Erika Cecchin, Giorgio Giorda, Roberto Sorio, Simona Scalone, Elena De Mattia, Rossana Roncato, Sara Gagno, Elena Poletto, Loredana Romanato, Fabrizio Ecca, Vincenzo Canzonieri, Giuseppe Toffoli
Published 2019-10-01

IL15RA and SMAD3 Genetic Variants Predict Overall Survival in Metastatic Colorectal Cancer Patients Treated with FOLFIRI Therapy: A New Paradigm

by Elena De Mattia, Jerry Polesel, Rossana Roncato, Adrien Labriet, Alessia Bignucolo, Sara Gagno, Angela Buonadonna, Mario D’Andrea, Eric Lévesque, Derek Jonker, Félix Couture, Chantal Guillemette, Erika Cecchin, Giuseppe Toffoli
Published 2021-04-01

Pharmacogenetics Biomarkers and Their Specific Role in Neoadjuvant Chemoradiotherapy Treatments: An Exploratory Study on Rectal Cancer Patients

by Eva Dreussi, Erika Cecchin, Jerry Polesel, Vincenzo Canzonieri, Marco Agostini, Caterina Boso, Claudio Belluco, Angela Buonadonna, Sara Lonardi, Francesca Bergamo, Sara Gagno, Elena De Mattia, Salvatore Pucciarelli, Antonino De Paoli, Giuseppe Toffoli
Published 2016-09-01

FARMAPRICE: A Pharmacogenetic Clinical Decision Support System for Precise and Cost-Effective Therapy

by Rossana Roncato, Lisa Dal Cin, Silvia Mezzalira, Francesco Comello, Elena De Mattia, Alessia Bignucolo, Lorenzo Giollo, Simone D’Errico, Antonio Gulotta, Luca Emili, Vincenzo Carbone, Michela Guardascione, Luisa Foltran, Giuseppe Toffoli, Erika Cecchin
Published 2019-04-01

Improved Progression-Free Survival in Irinotecan-Treated Metastatic Colorectal Cancer Patients Carrying the HNF1A Coding Variant p.I27L

by Adrien Labriet, Adrien Labriet, Elena De Mattia, Erika Cecchin, Éric Lévesque, Éric Lévesque, Derek Jonker, Félix Couture, Félix Couture, Angela Buonadonna, Mario D’Andrea, Lyne Villeneuve, Lyne Villeneuve, Giuseppe Toffoli, Chantal Guillemette, Chantal Guillemette
Published 2017-10-01

Clonal Selection of a Novel Deleterious TP53 Somatic Mutation Discovered in ctDNA of a KIT/PDGFRA Wild-Type Gastrointestinal Stromal Tumor Resistant to Imatinib

by Chiara Dalle Fratte, Michela Guardascione, Elena De Mattia, Eugenio Borsatti, Roberta Boschetto, Angelo Farruggio, Vincenzo Canzonieri, Vincenzo Canzonieri, Loredana Romanato, Rachele Borsatti, Sara Gagno, Elena Marangon, Maurizio Polano, Angela Buonadonna, Giuseppe Toffoli, Erika Cecchin
Published 2020-02-01

Germline Polymorphisms in the Nuclear Receptors PXR and VDR as Novel Prognostic Markers in Metastatic Colorectal Cancer Patients Treated With FOLFIRI

by Elena De Mattia, Jerry Polesel, Rossana Roncato, Adrien Labriet, Alessia Bignucolo, Eva Dreussi, Loredana Romanato, Michela Guardascione, Angela Buonadonna, Mario D'Andrea, Eric Lévesque, Derek Jonker, Félix Couture, Chantal Guillemette, Erika Cecchin, Giuseppe Toffoli
Published 2019-11-01

Association of STAT-3 rs1053004 and VDR rs11574077 With FOLFIRI-Related Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients

by Elena De Mattia, Erika Cecchin, Marcella Montico, Adrien Labriet, Chantal Guillemette, Eva Dreussi, Rossana Roncato, Alessia Bignucolo, Angela Buonadonna, Mario D’Andrea, Luigi Coppola, Sara Lonardi, Eric Lévesque, Derek Jonker, Félix Couture, Giuseppe Toffoli
Published 2018-04-01

HLA-G 3'UTR Polymorphisms Impact the Prognosis of Stage II-III CRC Patients in Fluoropyrimidine-Based Treatment.

by Marica Garziera, Ettore Bidoli, Erika Cecchin, Enrico Mini, Stefania Nobili, Sara Lonardi, Angela Buonadonna, Domenico Errante, Nicoletta Pella, Mario D'Andrea, Francesco De Marchi, Antonino De Paoli, Chiara Zanusso, Elena De Mattia, Renato Tassi, Giuseppe Toffoli
Published 2015-01-01

A Clinical-Genetic Score to Identify Surgically Resected Colorectal Cancer Patients Benefiting From an Adjuvant Fluoropyrimidine-Based Therapy

by Elena De Mattia, Eva Dreussi, Marcella Montico, Sara Gagno, Chiara Zanusso, Luca Quartuccio, Salvatore De Vita, Michela Guardascione, Angela Buonadonna, Mario D’Andrea, Nicoletta Pella, Adolfo Favaretto, Enrico Mini, Stefania Nobili, Loredana Romanato, Erika Cecchin, Giuseppe Toffoli
Published 2018-10-01