Managing clustering effects and learning effects in the design and analysis of multicentre randomised trials: a survey to establish current practice

Managing clustering effects and learning effects in the design and analysis of multicentre randomised trials: a survey to establish current practice

Abstract Background Patient outcomes can depend on the treating centre, or health professional, delivering the intervention. A health professional’s skill in delivery improves with experience, meaning that outcomes may be associated with learning. Considering differences in intervention delivery at...

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Bibliographic Details
Main Authors: Elizabeth J. Conroy, Jane M. Blazeby, Girvan Burnside, Jonathan A. Cook, Carrol Gamble
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Trials
Subjects:
Trials, Clinical Trials Unit, Clinical trial, Randomised controlled trial, Complex intervention
Surgical intervention
Trial design
Trial analysis
Survey
Clustering
Online Access:http://link.springer.com/article/10.1186/s13063-020-04318-x

Internet

http://link.springer.com/article/10.1186/s13063-020-04318-x

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