Quantitative Phase Imaging of Spreading Fibroblasts Identifies the Role of Focal Adhesion Kinase in the Stabilization of the Cell Rear

Quantitative Phase Imaging of Spreading Fibroblasts Identifies the Role of Focal Adhesion Kinase in the Stabilization of the Cell Rear

Cells attaching to the extracellular matrix spontaneously acquire front–rear polarity. This self-organization process comprises spatial activation of polarity signaling networks and the establishment of a protruding cell front and a non-protruding cell rear. Cell polarization also involves the reorg...

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Bibliographic Details
Main Authors: Olga Ramaniuk, Zuzana Klímová, Tomáš Groušl, Tomáš Vomastek
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biomolecules
Subjects:
coherence-controlled holographic microscopy
quantitative phase imaging
cell dry mass
focal adhesion kinase
Rack1
extracellular matrix
Online Access:https://www.mdpi.com/2218-273X/10/8/1089

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https://www.mdpi.com/2218-273X/10/8/1089

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