Quantitative Phase Imaging of Spreading Fibroblasts Identifies the Role of Focal Adhesion Kinase in the Stabilization of the Cell Rear

by Olga Ramaniuk, Zuzana Klímová, Tomáš Groušl, Tomáš Vomastek
Published 2020-07-01

Evolutionarily conserved 5'-3' exoribonuclease Xrn1 accumulates at plasma membrane-associated eisosomes in post-diauxic yeast.

by Tomas Grousl, Miroslava Opekarová, Vendula Stradalova, Jiri Hasek, Jan Malinsky
Published 2015-01-01

Heat shock-induced accumulation of translation elongation and termination factors precedes assembly of stress granules in S. cerevisiae.

by Tomas Grousl, Pavel Ivanov, Ivana Malcova, Petr Pompach, Ivana Frydlova, Renata Slaba, Lenka Senohrabkova, Lenka Novakova, Jiri Hasek
Published 2013-01-01

Mmi1, the yeast homologue of mammalian TCTP, associates with stress granules in heat-shocked cells and modulates proteasome activity.

by Mark Rinnerthaler, Renata Lejskova, Tomas Grousl, Vendula Stradalova, Gino Heeren, Klaus Richter, Lore Breitenbach-Koller, Jan Malinsky, Jiri Hasek, Michael Breitenbach
Published 2013-01-01

Cellular sequestrases maintain basal Hsp70 capacity ensuring balanced proteostasis

by Chi-ting Ho, Tomas Grousl, Oren Shatz, Areeb Jawed, Carmen Ruger-Herreros, Marije Semmelink, Regina Zahn, Karsten Richter, Bernd Bukau, Axel Mogk
Published 2019-10-01

Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding

by Sophia Ungelenk, Fatemeh Moayed, Chi-Ting Ho, Tomas Grousl, Annette Scharf, Alireza Mashaghi, Sander Tans, Matthias P. Mayer, Axel Mogk, Bernd Bukau
Published 2016-11-01