TRAIL/TRAIL receptor system and susceptibility to multiple sclerosis.

The TNF-related apoptosis inducing ligand (TRAIL)/TRAIL receptor system participates in crucial steps in immune cell activation or differentiation. It is able to inhibit proliferation and activation of T cells and to induce apoptosis of neurons and oligodendrocytes, and seems to be implicated in aut...

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Main Authors: Carlos López-Gómez, Oscar Fernández, Juan Antonio García-León, María Jesús Pinto-Medel, Begoña Oliver-Martos, Jesús Ortega-Pinazo, Margarita Suardíaz, Lucía García-Trujillo, Cristina Guijarro-Castro, Julián Benito-León, Isidro Prat, Jezabel Varadé, Roberto Álvarez-Lafuente, Elena Urcelay, Laura Leyva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21814551/pdf/?tool=EBI