Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer’s Disease

by Juan Antonio Garcia-Leon, Laura Caceres-Palomo, Elisabeth Sanchez-Mejias, Marina Mejias-Ortega, Cristina Nuñez-Diaz, Juan Jose Fernandez-Valenzuela, Raquel Sanchez-Varo, Jose Carlos Davila, Javier Vitorica, Antonia Gutierrez
Published 2020-09-01

TRAIL/TRAIL receptor system and susceptibility to multiple sclerosis.

by Carlos López-Gómez, Oscar Fernández, Juan Antonio García-León, María Jesús Pinto-Medel, Begoña Oliver-Martos, Jesús Ortega-Pinazo, Margarita Suardíaz, Lucía García-Trujillo, Cristina Guijarro-Castro, Julián Benito-León, Isidro Prat, Jezabel Varadé, Roberto Álvarez-Lafuente, Elena Urcelay, Laura Leyva
Published 2011-01-01

SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells

by Juan Antonio García-León, Manoj Kumar, Ruben Boon, David Chau, Jennifer One, Esther Wolfs, Kristel Eggermont, Pieter Berckmans, Nilhan Gunhanlar, Femke de Vrij, Bas Lendemeijer, Benjamin Pavie, Nikky Corthout, Steven A. Kushner, José Carlos Dávila, Ivo Lambrichts, Wei-Shou Hu, Catherine M. Verfaillie
Published 2018-02-01

Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer’s disease-like pathology

by David Baglietto-Vargas, Stefania Forner, Lena Cai, Alessandra C. Martini, Laura Trujillo-Estrada, Vivek Swarup, Marie Minh Thu Nguyen, Kelly Do Huynh, Dominic I. Javonillo, Kristine Minh Tran, Jimmy Phan, Shan Jiang, Enikö A. Kramár, Cristina Nuñez-Diaz, Gabriela Balderrama-Gutierrez, Franklin Garcia, Jessica Childs, Carlos J. Rodriguez-Ortiz, Juan Antonio Garcia-Leon, Masashi Kitazawa, Mohammad Shahnawaz, Dina P. Matheos, Xinyi Ma, Celia Da Cunha, Ken C. Walls, Rahasson R. Ager, Claudio Soto, Antonia Gutierrez, Ines Moreno-Gonzalez, Ali Mortazavi, Andrea J. Tenner, Grant R. MacGregor, Marcelo Wood, Kim N. Green, Frank M. LaFerla
Published 2021-04-01