Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm.

Saposin-like proteins (SAPLIPs) from soil-transmitted helminths play pivotal roles in host-pathogen interactions and have a high potential as targets for vaccination against parasitic diseases. We have identified two non-orthologous SAPLIPs from human and dog hookworm, Na-SLP-1 and Ac-SLP-1, and sol...

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Bibliographic Details
Main Authors: Charlene Willis, Conan K Wang, Asiah Osman, Anne Simon, Darren Pickering, Jason Mulvenna, Alan Riboldi-Tunicliffe, Malcolm K Jones, Alex Loukas, Andreas Hofmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3184995?pdf=render