Vaccination with <i>Schistosoma mansoni</i> Cholinesterases Reduces the Parasite Burden and Egg Viability in a Mouse Model of Schistosomiasis

by Bemnet A. Tedla, Darren Pickering, Luke Becker, Alex Loukas, Mark S. Pearson
Published 2020-04-01

Complement inhibitors from scabies mites promote streptococcal growth--a novel mechanism in infected epidermis?

by Angela Mika, Simone L Reynolds, Darren Pickering, David McMillan, Kadaba S Sriprakash, David J Kemp, Katja Fischer
Published 2012-01-01

Novel cholinesterase paralogs of Schistosoma mansoni have perceived roles in cholinergic signalling and drug detoxification and are essential for parasite survival.

by Bemnet A Tedla, Javier Sotillo, Darren Pickering, Ramon M Eichenberger, Stephanie Ryan, Luke Becker, Alex Loukas, Mark S Pearson
Published 2019-12-01

Compounds Derived from the Bhutanese Daisy, Ajania nubigena, Demonstrate Dual Anthelmintic Activity against Schistosoma mansoni and Trichuris muris.

by Phurpa Wangchuk, Mark S Pearson, Paul R Giacomin, Luke Becker, Javier Sotillo, Darren Pickering, Michael J Smout, Alex Loukas
Published 2016-08-01

Monoclonal Antibodies Targeting an <i>Opisthorchis viverrini</i> Extracellular Vesicle Tetraspanin Protect Hamsters against Challenge Infection

by Wuttipong Phumrattanaprapin, Mark Pearson, Darren Pickering, Bemnet Tedla, Michael Smout, Sujittra Chaiyadet, Paul J. Brindley, Alex Loukas, Thewarach Laha
Published 2021-07-01

<i>Schistosoma Haematobium</i> Extracellular Vesicle Proteins Confer Protection in a Heterologous Model of Schistosomiasis

by Gebeyaw G. Mekonnen, Bemnet A. Tedla, Darren Pickering, Luke Becker, Lei Wang, Bin Zhan, Maria Elena Bottazzi, Alex Loukas, Javier Sotillo, Mark S. Pearson
Published 2020-07-01

Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm.

by Charlene Willis, Conan K Wang, Asiah Osman, Anne Simon, Darren Pickering, Jason Mulvenna, Alan Riboldi-Tunicliffe, Malcolm K Jones, Alex Loukas, Andreas Hofmann
Published 2011-01-01

Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases.

by Madhu K Sundaraneedi, Bemnet A Tedla, Ramon M Eichenberger, Luke Becker, Darren Pickering, Michael J Smout, Siji Rajan, Phurpa Wangchuk, F Richard Keene, Alex Loukas, J Grant Collins, Mark S Pearson
Published 2017-12-01