Release of Major Peanut Allergens from Their Matrix under Various pH and Simulated Saliva Conditions—Ara h2 and Ara h6 Are Readily Bio-Accessible

Release of Major Peanut Allergens from Their Matrix under Various pH and Simulated Saliva Conditions—Ara h2 and Ara h6 Are Readily Bio-Accessible

The oral mucosa is the first immune tissue that encounters allergens upon ingestion of food. We hypothesized that the bio-accessibility of allergens at this stage may be a key determinant for sensitization. Light roasted peanut flour was suspended at various pH in buffers mimicking saliva. Protein c...

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Bibliographic Details
Main Authors: Stef J. Koppelman, Mieke Smits, Monic Tomassen, Govardus A.H. de Jong, Joe Baumert, Steve L. Taylor, Renger Witkamp, Robert Jan Veldman, Raymond Pieters, Harry Wichers
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Nutrients
Subjects:
peanut
Arachis hypogaea
allergen
bio-accessibility
saliva
Online Access:http://www.mdpi.com/2072-6643/10/9/1281

Internet

http://www.mdpi.com/2072-6643/10/9/1281

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