Protease-Specific Biomarkers to Analyse Protease Inhibitors for Emphysema Associated with Alpha 1-Antitrypsin Deficiency. An Overview of Current Approaches

Protease-Specific Biomarkers to Analyse Protease Inhibitors for Emphysema Associated with Alpha 1-Antitrypsin Deficiency. An Overview of Current Approaches

As a known genetic cause of chronic obstructive pulmonary disease (COPD), alpha1-antitrypsin deficiency (AATD) can cause severe respiratory problems at a relatively young age. These problems are caused by decreased or absent levels of alpha1-antitrypsin (AAT), an antiprotease which is primarily func...

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Bibliographic Details
Main Authors: Simona Viglio, Elisabeth G. Bak, Iris G. M. Schouten, Paolo Iadarola, Jan Stolk
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
alpha1-antitrypsin
AAT
alpha1-antitrypsin deficiency
AATD
human neutrophil elastase
proteinase 3
Online Access:https://www.mdpi.com/1422-0067/22/3/1065

Internet

https://www.mdpi.com/1422-0067/22/3/1065

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