Methods of Purification and Application Procedures of Alpha1 Antitrypsin: A Long-Lasting History

by Simona Viglio, Paolo Iadarola, Maura D’Amato, Jan Stolk
Published 2020-09-01

Transitioning Clinical Data into Patient Care: Recent Real-Life Experiences with Alpha 1

by Jan Stolk, Berend Stoel, David Parr, Joachim H. Ficker, Charlie Strange
Published 2017-10-01

Regional lung densities in alpha-1 antitrypsin deficiency compared to predicted values

by Berend C. Stoel, Jan Stolk, M. Els Bakker, David G. Parr
Published 2019-02-01

Protease-Specific Biomarkers to Analyse Protease Inhibitors for Emphysema Associated with Alpha 1-Antitrypsin Deficiency. An Overview of Current Approaches

by Simona Viglio, Elisabeth G. Bak, Iris G. M. Schouten, Paolo Iadarola, Jan Stolk
Published 2021-01-01

Functional characterisation of bone marrow-derived mesenchymal stromal cells from COPD patients

by Winifred Broekman, Helene Roelofs, Maria C. Zarcone, Christian Taube, Jan Stolk, Pieter S. Hiemstra
Published 2016-06-01

Prediction of lung function and lung density of young adults who had bronchopulmonary dysplasia

by Helger Y. Santema, Jan Stolk, Mady Los, Berend C. Stoel, Roula Tsonaka, Istvan T. Merth
Published 2020-10-01

Retinoid treatment of Emphysema in Patients on the Alpha-1 International Registry. The REPAIR study: study design, methodology and quality control of study assessments

by Jan Stolk, Brendan G. Cooper, Berend Stoel, Alexis Rames, Olga Rutman, Sherif Soliman, Robert Stockley
Published 2010-12-01

The Course of AαVal541 as a Proteinase 3 Specific Neo-Epitope after Alpha-1-Antitrypsin Augmentation in Severe Deficient Patients

by Iris G. M. Schouten, Richard A. Mumford, Dirk Jan A. R. Moes, Pieter S. Hiemstra, Jan Stolk
Published 2021-07-01

Respiratory Proteomics Today: Are Technological Advances for the Identification of Biomarker Signatures Catching up with Their Promise? A Critical Review of the Literature in the D...

by Simona Viglio, Jan Stolk, Paolo Iadarola, Serena Giuliano, Maurizio Luisetti, Roberta Salvini, Marco Fumagalli, Anna Bardoni
Published 2014-01-01

Modulation of Airway Epithelial Innate Immunity and Wound Repair by M(GM-CSF) and M(M-CSF) Macrophages

by Sander van Riet, Annemarie van Schadewijk, Steve de Vos, Nick Vandeghinste, Robbert J. Rottier, Jan Stolk, Pieter S. Hiemstra, Padmini Khedoe
Published 2020-04-01

Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiationResearch in context

by John-Poul Ng-Blichfeldt, Anneke Schrik, Rosa K. Kortekaas, Jacobien A. Noordhoek, Irene H. Heijink, Pieter S. Hiemstra, Jan Stolk, Melanie Königshoff, Reinoud Gosens
Published 2018-10-01

Profiling the Proteome of Exhaled Breath Condensate in Healthy Smokers and COPD Patients by LC-MS/MS

by Carmine Tinelli, Paolo Iadarola, Federica Corana, Isa Cerveri, Laura Fregonese, Simona Viglio, Daniela Capuano, Pieter S. Hiemstra, Jan Stolk, Maurizio Luisetti, Fabio Ferrari, Marco Fumagalli
Published 2012-10-01

Identification of Novel Short C-Terminal Transcripts of Human SERPINA1 Gene.

by Nerea Matamala, Nupur Aggarwal, Paolo Iadarola, Marco Fumagalli, Gema Gomez-Mariano, Beatriz Lara, Maria Teresa Martinez, Isabel Cuesta, Jan Stolk, Sabina Janciauskiene, Beatriz Martinez-Delgado
Published 2017-01-01

Association of Lung Inflammatory Cells with Small Airways Function and Exhaled Breath Markers in Smokers - Is There a Specific Role for Mast Cells?

by Yvonne Nussbaumer-Ochsner, Jan Stolk, Luiz F Ferraz da Silva, Annemarie van Schadewijk, Ronald C de Jeu, Frans A Prins, Thais Mauad, Klaus F Rabe, Pieter S Hiemstra
Published 2015-01-01

Long-term effect of α1-antitrypsin augmentation therapy on the decline of FEV1 in deficient patients: an analysis of the AIR database

by Iris G.M. Schouten, Marise J. Kasteleyn, Roula Tsonaka, Robert Bals, Alice C. Turner, Ilaria Ferrarotti, Angelo G. Corsico, Beatriz Lara, Marc Miravitlles, Robert A. Stockley, Jan Stolk
Published 2021-08-01

Polymerization of misfolded Z alpha-1 antitrypsin protein lowers CX3CR1 expression in human PBMCs

by Srinu Tumpara, Matthias Ballmaier, Sabine Wrenger, Mandy König, Matthias Lehmann, Ralf Lichtinghagen, Beatriz Martinez-Delgado, Elena Korenbaum, David DeLuca, Nils Jedicke, Tobias Welte, Malin Fromme, Pavel Strnad, Jan Stolk, Sabina Janciauskiene
Published 2021-05-01

Protocol for the EARCO Registry: a pan-European observational study in patients with α1-antitrypsin deficiency

by Timm Greulich, Alan Altraja, Miriam Barrecheguren, Robert Bals, Jan Chlumsky, Joanna Chorostowska-Wynimko, Christian Clarenbach, Luciano Corda, Angelo Guido Corsico, Ilaria Ferrarotti, Cristina Esquinas, Caroline Gouder, Ana Hećimović, Aleksandra Ilic, Yavor Ivanov, Sabina Janciauskiene, Wim Janssens, Malcolm Kohler, Alvils Krams, Beatriz Lara, Ravi Mahadeva, Gerry McElvaney, Jean-François Mornex, Karen O'Hara, David Parr, Eava Piitulainen, Karin Schmid-Scherzer, Niels Seersholm, Robert A. Stockley, Jan Stolk, Maria Sucena, Hanan Tanash, Alice Turner, Ruxandra Ulmeanu, Marion Wilkens, Arzu Yorgancioğlu, Ana Zaharie, Marc Miravitlles
Published 2020-03-01

Research priorities in α1-antitrypsin deficiency: results of a patients' and healthcare providers' international survey from the EARCO Clinical Research Collaboration

by Miriam Barrecheguren, Karen O'Hara, Marion Wilkens, Jeanette Boyd, Ewa Kolda, Beatriz Lara, Joanna Chorostowska-Wynimko, Ilaria Ferrarotti, Jan Chlumský, Christian Clarenbach, Timm Greulich, Marc Miravitlles, Maria Sucena, Members of EARCO CRC Timm Greulich (Germany, co-chair) Marc Miravitlles (Spain co-chair). Steering committee:, Joanna Chorostowska-Wymiko (Poland), Ilaria Ferrarotti (Italy), Noel G. McElvaney (Ireland), Karen O'Hara (UKpatients' representative), Jan Stolk (Netherlands), Robert A. Stockley, Alice Turner (UK), Marion Wilkens (Germany patients' representative), EARCO members:, Angelo Corsico, Luciano Corda (Italy), Maria Sucena (Portugal), Miriam Barrecheguren (Spain ERS early career representative), Cristina Esquinas (Spain), David Parr, Beatriz Lara, Ravi Mahadeva (UK), Jan Chlumsky (Czech Republic), Sabina Janciauskiene, Robert Bals (Germany), Jens Ulrik Jensen (Denmark), Kostas Kostikas (Greece), Malcolm Kohler, Christian Clarenbach (Switzerland), Alan Altraja (Estonia), Wim Jenssens, Silvia Pérez-Bogerd (Belgium), Caroline Gouder (Malta), Ana Hecimovic (Croatia), Aleksandra Dudvarski (Serbia), Alvils Krams (Latvia), Ruxandra Ulmeanu, Ana Zaharie (Rumania), Jean-François Mornex (France), Arzu Yorgancioglu (Tukey), Karin Schmid-Scherzer (Austria), Hanan Tanash, Eeva Piitulainen (Sweden), Oleksandr Mazulov (Ukraine), Yavor Ivanov (Bulgaria)
Published 2020-12-01