Pioglitazone improves phagocytic activity of liver recruited macrophages in elderly mice possibly by promoting glucose catabolism

Recent studies have revealed that the immunological function of leukocytes is dependent on their cellular metabolism, and some researchers have advocated the beneficial effects of pioglitazone against sepsis in young mice, although bacterial infections are more prevalent in elderly hosts. Here, we i...

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Bibliographic Details
Main Authors: Masahiro Nakashima, Manabu Kinoshita, Hiroyuki Nakashima, Aya Kotani, Takuya Ishikiriyama, Shoichiro Kato, Sadayuki Hiroi, Shuhji Seki
Format: Article
Language:English
Published: SAGE Publishing 2019-08-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/1753425919849620