Immune Mechanisms Underlying Susceptibility to Endotoxin Shock in Aged Hosts: Implication in Age-Augmented Generalized Shwartzman Reaction

by Manabu Kinoshita, Masahiro Nakashima, Hiroyuki Nakashima, Shuhji Seki
Published 2019-07-01

Antitumor Immunity Produced by the Liver Kupffer Cells, NK Cells, NKT Cells, and CD8+ CD122+ T Cells

by Shuhji Seki, Hiroyuki Nakashima, Masahiro Nakashima, Manabu Kinoshita
Published 2011-01-01

Roles of Natural Killer T Cells and Natural Killer Cells in Kidney Injury

by Takahiro Uchida, Seigo Ito, Hiroo Kumagai, Takashi Oda, Hiroyuki Nakashima, Shuhji Seki
Published 2019-05-01

Involvement of the TNF and FasL produced by CD11b Kupffer cells/macrophages in CCl4-induced acute hepatic injury.

by Atsushi Sato, Hiroyuki Nakashima, Masahiro Nakashima, Masami Ikarashi, Kiyoshi Nishiyama, Manabu Kinoshita, Shuhji Seki
Published 2014-01-01

Pioglitazone improves phagocytic activity of liver recruited macrophages in elderly mice possibly by promoting glucose catabolism

by Masahiro Nakashima, Manabu Kinoshita, Hiroyuki Nakashima, Aya Kotani, Takuya Ishikiriyama, Shoichiro Kato, Sadayuki Hiroi, Shuhji Seki
Published 2019-08-01

Mouse CD11b+Kupffer Cells Recruited from Bone Marrow Accelerate Liver Regeneration after Partial Hepatectomy.

by Kiyoshi Nishiyama, Hiroyuki Nakashima, Masami Ikarashi, Manabu Kinoshita, Masahiro Nakashima, Suefumi Aosasa, Shuhji Seki, Junji Yamamoto
Published 2015-01-01

Activation of CD11b+ Kupffer cells/macrophages as a common cause for exacerbation of TNF/Fas-ligand-dependent hepatitis in hypercholesterolemic mice.

by Hiroyuki Nakashima, Yoshiko Ogawa, Satoshi Shono, Manabu Kinoshita, Masahiro Nakashima, Atsushi Sato, Masami Ikarashi, Shuhji Seki
Published 2013-01-01

A Combination of Pre- and Post-Exposure Ascorbic Acid Rescues Mice from Radiation-Induced Lethal Gastrointestinal Damage

by Yukihiro Takahashi, Shuhji Seki, Daizoh Saitoh, Takeyuki Obara, Tomohito Sato, Tetsuo Yamamoto, Manabu Kinoshita, Yasutoshi Ito
Published 2013-09-01

Repeated administration of alpha-galactosylceramide ameliorates experimental lupus nephritis in mice

by Takahiro Uchida, Hiroyuki Nakashima, Akira Yamagata, Seigo Ito, Takuya Ishikiriyama, Masahiro Nakashima, Shuhji Seki, Hiroo Kumagai, Naoki Oshima
Published 2018-05-01

Treatment of irradiated mice with high-dose ascorbic acid reduced lethality.

by Tomohito Sato, Manabu Kinoshita, Tetsuo Yamamoto, Masataka Ito, Takafumi Nishida, Masaru Takeuchi, Daizoh Saitoh, Shuhji Seki, Yasuo Mukai
Published 2015-01-01

Contrasting functional responses of resident Kupffer cells and recruited liver macrophages to irradiation and liver X receptor stimulation.

by Takuya Ishikiriyama, Hiroyuki Nakashima, Kaori Endo-Umeda, Masahiro Nakashima, Seigo Ito, Manabu Kinoshita, Masami Ikarashi, Makoto Makishima, Shuhji Seki
Published 2021-01-01

The Efficacy of Posttreatment with Synthetic C-Reactive Protein in Murine Bacterial Peritonitis via Activation of FcγRI-Expressing Kupffer Cells

by Manabu Kinoshita, Seigo Ito, Takuya Ishikiriyama, Kumiko Sekiguchi, Ryota Yamaguchi, Ryoichi Tsuruhara, Akihisa Matsuda, Kazuki Koiwa, Masahiro Nakashima, Hiroyuki Nakashima, Masao Miyashita, Shuhji Seki
Published 2021-05-01