BCL2 Family, Mitochondrial Apoptosis, and Beyond

BCL2 Family, Mitochondrial Apoptosis, and Beyond

Apoptosis is a morphologically and biochemically distinct form of cell death that plays an essential role in development, immune response, and tissue homeostasis. Diminished apoptosis is also considered a hallmark of cancer whereas many cancer treatments induce apoptosis in susceptible cells. Classi...

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Bibliographic Details
Main Authors: Haiming Dai, X Wei Meng, Scott H Kaufmann
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Cancer Translational Medicine
Subjects:
Apoptosis
B-cell lymphoma-2 family
BAK/BAX activation
BH3 domain
mitochondrial outer membrane permeabilization
Online Access:http://www.cancertm.com/article.asp?issn=2395-3977;year=2016;volume=2;issue=1;spage=7;epage=20;aulast=Dai

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http://www.cancertm.com/article.asp?issn=2395-3977;year=2016;volume=2;issue=1;spage=7;epage=20;aulast=Dai

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