DNA Damage: A Main Determinant of Vascular Aging

DNA Damage: A Main Determinant of Vascular Aging

Vascular aging plays a central role in health problems and mortality in older people. Apart from the impact of several classical cardiovascular risk factors on the vasculature, chronological aging remains the single most important determinant of cardiovascular problems. The causative mechanisms by w...

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Bibliographic Details
Main Authors: Paula K. Bautista-Niño, Eliana Portilla-Fernandez, Douglas E. Vaughan, A. H. Jan Danser, Anton J. M. Roks
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:International Journal of Molecular Sciences
Subjects:
vascular
aging
endothelium
genomic instability
DNA damage
senescence
PAI-1
eNOS
phosphodiesterase
dietary restriction
Online Access:http://www.mdpi.com/1422-0067/17/5/748

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http://www.mdpi.com/1422-0067/17/5/748

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