A Combination of Pre- and Post-Exposure Ascorbic Acid Rescues Mice from Radiation-Induced Lethal Gastrointestinal Damage

A Combination of Pre- and Post-Exposure Ascorbic Acid Rescues Mice from Radiation-Induced Lethal Gastrointestinal Damage

The development of an effective therapy for radiation-induced gastrointestinal damage is important, because it is currently a major complication of treatment and there are few effective therapies available. Although we have recently demonstrated that pretreatment with ascorbic acid attenuates lethal...

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Bibliographic Details
Main Authors: Yukihiro Takahashi, Shuhji Seki, Daizoh Saitoh, Takeyuki Obara, Tomohito Sato, Tetsuo Yamamoto, Manabu Kinoshita, Yasutoshi Ito
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:International Journal of Molecular Sciences
Subjects:
ascorbic acid
abdominal radiation
citrulline
radiation-induced gastrointestinal damage
post-irradiation treatment with ascorbic acid
Online Access:http://www.mdpi.com/1422-0067/14/10/19618

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http://www.mdpi.com/1422-0067/14/10/19618

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