Feasibility of Immunohistochemical p16 Staining in the Diagnosis of Human Papillomavirus Infection in Patients With Squamous Cell Carcinoma of the Head and Neck: A Systematic Review and Meta-Analysis

Feasibility of Immunohistochemical p16 Staining in the Diagnosis of Human Papillomavirus Infection in Patients With Squamous Cell Carcinoma of the Head and Neck: A Systematic Review and Meta-Analysis

Human papillomavirus (HPV) is a risk factor for squamous cell carcinoma of the head and neck (HNSCC). This study aimed to investigate the feasibility of IHC- p16INK4a (p16) as an alternative modality for diagnosing HPV infection. We searched PubMed, EMBASE, Web of Science, and Cochrane library for s...

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Bibliographic Details
Main Authors: Huanhuan Wang, Yuyu Zhang, Wei Bai, Bin Wang, Jinlong Wei, Rui Ji, Ying Xin, Lihua Dong, Xin Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
human papillomavirus
squamous cell cancers of the head and neck
immunohistochemical staining
p16
meta-analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.524928/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.524928/full

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