Biochemical characterization of cholesteryl ester transfer protein inhibitors

Biochemical characterization of cholesteryl ester transfer protein inhibitors

Cholesteryl ester transfer protein (CETP) has been identified as a novel target for increasing HDL cholesterol levels. In this report, we describe the biochemical characterization of anacetrapib, a potent inhibitor of CETP. To better understand the mechanism by which anacetrapib inhibits CETP activi...

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Bibliographic Details
Main Authors: Mollie Ranalletta, Kathleen K. Bierilo, Ying Chen, Denise Milot, Qing Chen, Elaine Tung, Caroline Houde, Nadine H. Elowe, Margarita Garcia-Calvo, Gene Porter, Suzanne Eveland, Betsy Frantz-Wattley, Mike Kavana, George Addona, Peter Sinclair, Carl Sparrow, Edward A. O'Neill, Ken S. Koblan, Ayesha Sitlani, Brian Hubbard, Timothy S. Fisher
Format: Article
Language:English
Published: Elsevier 2010-09-01
Series:Journal of Lipid Research
Subjects:
triglyceride
anacetrapib
torcetrapib
dalcetrapib
atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520423041

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http://www.sciencedirect.com/science/article/pii/S0022227520423041

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